WOLFRAM

計算生物学

生物系および生化学系をモデル化し,そのシミュレーションを実行し,可視化します.反応動力学もモデル化し,そのシミュレーションを実行します.

Glycolysis: Study Oscillations in Yeast Cells

Glycolytic oscillations in yeast cells of the species Saccharomyces cerevisiae is a well-studied phenomenon. This example simulates the oscillations near a so-called Hopf bifurcation. Changing a parameter slightly around the bifurcation point qualitatively changes the behavior of the system.

この例を実行するためには以下が必要です.

System ModelerとMathematicaの最新版

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Import SBML Models

Easily import the model in the Systems Biology Markup Language (SBML) format.

Simulate Different Scenarios

Compare how small changes in the bifurcation parameter affect the oscillations of protein and molecule concentrations.

BioChem example model
for yeast glycolysis
Cytosol component
ATP oscillations on different
sides of the bifurcation point

Visualize Biological Reaction Networks

Use the built-in BioChem library to visualize and simulate the model.

Hynne et al., 2001. Full-scale model of glycolysis in Saccharomyces cerevisiae.
Biophys Chem. 94(1–2):121–63.